How do I clean my local disks?

This alert recently came up on my computer with my anti-virus system:

a variant of Win32/Adware.Virtumonde.NEG application found in operating memory. The file can be deleted. It is strongly recommended that you back up any crucial data before you proceed. No action can be taken while the file is in memory. Click "Leave" to continue and subsequently run the cleaning of all local disks. System memory infection originated from file C:\WINDOWS\system32\cbXQhFWp.dll.

I clicked leave, got all my critical data backed up, but I don't know how to clean local disks? Any hints?

c g2009-02-28T15:24:23Z

Favorite Answer

Boot Window's into safe mode(At boot screen press delete or F1 or what ever it says)When in safe mode go to start>Control panel>Now double click on system,,then click top left tab(System Restore)Click tick box on left(Turn off System Restore)Now run your Anti-Virus & spy-ware programs let them remove all infection..when done reboot computer re-run Anti-Virus & spy-ware programs they should now be clean,,If clean turn system restore back on..Hopefully all should be well...