vasomotor center depression?

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Cardiovascular depression may occur following depression of the medullary vasomotor centers; patients with underlying congestive heart failure (CHF) are more susceptible to these effects.
At higher doses, cardiac contractility and vascular tone are compromised, which may cause cardiovascular collapse.

Overdose with barbiturate may be associated with multiple complications, the most common of which is pneumonia. Other life-threatening complications may include acute renal failure, pulmonary edema,bradycardia,arrhythmias,(poor heart pumping function), the sequelae of hypotension(low blood pressure) and respiratory depression(hypoventilation).

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There are a number of facilities within the frame that keep an eye on blood strain and center fee. The first is the vagus nerve (cranial nerve 10). If this nerve is stimulate equivalent to whilst a individual traces to take a bowel motion, coughs, sneezes, or holds their breath towards a drive, this nerve will get prompted. It sends an immediate sign to the mind to slower the guts fee. This is whilst the parasympathetic anxious procedure kicks in. The individual might be bradycardic and might increase ectopy on an EKG track founded at the sluggish fee (and accompanying hypoxia). This ectopy might be a PVC (untimely ventricular contraction) or a PAC (untimely atrial contraction). This is the frame's technique to stimulate the guts. Another vasomotor core is the baroreceptors which can be placed within the aorta of the guts and carotid arteries of the neck. When those are prompted, the guts fee and blood strain decrease. Once once more, the identical ectopy might look on an EKG. Those 2 matters are the main vasomotor facilities within the frame for the parasympathetic anxious procedure that allows you to sluggish the guts fee and the blood strain. Hope this is helping....Show more

Lower heart rate (bradycardia) + low blood pressure (hypotension)....Show more