Explain as best as you can the interaction between B and T cells in the specific immune responses.?

T cells (3types ; T helper cells, T killer cells, T suppressor cells) and B cells both act simultaneously against specific foreign invader (ie. virus, bacteria etc). Any foreign invader can provoke both cellular and humoral immune response. As invaders enter the body via blood, macrophages phagocytizes some of them and their debries are represented to T helper cells to convey the information of body being invaded. Now theT helper cells by secreting lymphokines and interlekins stimulates

(1) B cells to produce plasma cells, which in turn produces antibodies to kill or neutralize invaders in blood. This is called humoral immune response.

(2) T killer cells to kill the infected cell along with the invader,as some invader might had escaped from humoral immune response and invaded the tissue. This is called cellular immune response.

The T suppressor cell checks the overactivity of T helper and T killer cells.

THATS ALL

B cells "show" antigen to T helper cells. T helpers recognize the antigen with their CD4 molecules on their surfaces, sending a signal to the T cells to start making cytokines (many interleukins which have different jobs). For example, interleukins 4 and 13 act on B cells to signal class switching to IgE in allergic reactions (initially, the B cells only have surface IgM, and little or no other types of antibodies). Certain cytokines produce other antibodies as well.

So the B cells can start making and secreting other types of antibodies now which are specific to pretty much any foreign material presented to the body.

So T helper cells are so called because they "help" B cells in the immune response.

The T cells signal the B cells to being producing antibodies against the invader.