Manga were the guy is over protective like in charming junkie?

I recommend fate stay night!~ It's great!

The story takes place in an ordinary Japanese town, Fuyuki City. Hidden from society, there has been a deadly war going on in this town. Seven sorcerers known as "Masters" summon a powerful familiar called "Servants" and they all fight each other till the last one. The last one is said to attain the Holy Grail which will grant them a wish. Only a few knows when this War started and what the Holy Grail is, but the war was about to begin again this year. The main character is Emiya Shirou, who lost his parents in a fire and was adopted by a man who called himself a sorcerer. Admiring his step father, he has been training himself to be a sorcerer. However, he had no talent and he could barely use one type of sorcery. His step father has already passed away, and today he's a sorcerer without any skills or knowledge. He is involved in the War of the Holy Grail when he accidentally summons Saber, who is said to be the strongest servant of all.

And also Ouran High School Host Club ~

One day, Haruhi, a scholarship student at exclusive Ouran High School, breaks an $80,000 vase that belongs to the "Host Club", a mysterious campus group consisting of six super-rich (and gorgeous) guys. To pay back the damages, she is forced to work for the club, and it's there that she discovers just how wealthy the boys are and how different they are from everybody else.

Have you watched Ouran High School Host Club? Its almost insane how much that matches your description. It is one of my all-time favorites. It is very romantic and quirky, and for me, it is one of the best comedies AND love stories. Now I'm all excited, I think ill watch it again. Also, gender is a HUGE part of this anime. I am not familiar with the term "gender blender", but I have to assume that this anime would fall into that category. (Main character is thought to be of the opposite sex by almost everyone, and goes along with it...)

Hope you really like it! :)