Wich US city has the best nightlife?

I would argue Las Vegas, since there is a lot of 24-hour entertainment, high end establishments, and headliner acts to see. 

Many establishments in New York are 24-hour and it has Broadway, but it is New York, and I would rather cut my own balls off then ever return to that shithole.  Los Angeles is the second largest city but everything closes at 2AM, so not that.  Chicago is the third largest city but I think is too blue collar to be a real high life nighttime city. 

Miami and New Orleans are pretty fun, though.

The cities that are generally best known for the best nightlife are NYC, Vegas, and Miami.  I think you can make a case for any of them as the very best since that's pretty subjective anyway.  They each have their own little unique aspects too. 

Vegas by far for sure

New York, the city that never sleeps MUST be it. I have only travelled thru airports. BUT have read about the nightlife. It is a CLASSIC city.

No clue 😂 but I think any city really . Just have to know beforehand