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molecular genetics exons and introns?
A Drosophila gene was initially identified as having three exons and two introns. The exons
are 200, 300, and 400 bp, while the introns are 500 bp and 600 bp.
a) Draw this gene, showing 5’ and 3’ ends, the promoter, exons, introns and the transcription
start site.
b) Draw the pre-mRNA of the above gene.
c) Two mRNAs have been identified that are encoded by this gene. One mRNA is 900 bp in
length (excluding the polyA tail) and the other is 600 bp in length (also excluding the polyA
tail). Use your drawing to show how the two mRNAs are made.
1 AnswerBiology1 decade agomolecular genetics question?
Gene X encodes an enzyme that is expressed in the skin, the brain and the heart. Skinny,
brainy, hearty are three genes that encode three tissue-specific transcription factors that
activate the expression of gene X in the skin, the brain, and the heart, respectively. A student
has isolated a mutant mouse in which the enzyme activity of X is greatly reduced in the
brain, but is normal in the skin and the heart. The expression level of skinny, brainy, and
hearty is normal in this mouse and there is no mutation in any of the three genes. Propose a
simple explanation for the lack of X activity in the brain in the mutant mouse. (Assume that
there is no alternative splicing for gene X in the three tissues.)
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