Any good methods to increase your chances at making a profit in KENO?

Keno has the worst return of any of the popular casino games. If you are going to play it, you should play only for low stakes, wagering money that you can afford to lose.

You can improve your potential return by examining the pay tables at your casino. Some games play a lot more than others, although I've never seen one that comes close to favoring the player. On the machines that I see most frequently, there is a slight advantage to playing 8 numbers, but I'm sure that this varies by game manufacturer. The pattern doesn't have anything to do with your potential winnings. Play for fun or as you would play a state lottery. Risk small amounts only! Remember, you are probably giving away 15 to 20% of your bet each time.