Does Luvox interact with thioridazine?

Yes they do interact. Fluvoxamine(Luvox) affects the pharmaco-kinetics of Thioridazine causing an increase in the plasma concentrations of the latter and it's metabolites (mesoridazine & sulforidazine). This can result in serious cardiovascular side-effects. Avoid the combo.

The following is a list of drugs to avoid when taking Luvox:

- cisapride

- astemizole (Hisminal)

- terfenadine (Seldane)

- tizanidine

- pimozide (Orap)

- Any Monoamine Oxide Inhibitor (MAOI) eg. Nardil, Parnate, Marplan

- tryptophan

- triptans (sumatriptan etc.)

- benzodiazepines that are metabolized by hepatic oxidation (alprazolam, diazepam, midazolam, triazolam)

- theophylline

- warfarin

- aspirin & NSAIDS (increased risk of bleeding)

Cheers,

AJ

EDIT: add beta-blockers to the list above as suggested by the previous poster

NO you cannot take take them together

Do not take thioridazine with any of the following drugs: psychiatric medications such as fluoxetine (Prozac), paroxetine (Paxil, Paxil CR), and fluvoxamine (Luvox); or blood pressure medications such as pindolol (Visken) or propranolol (Inderal, Inderal LA, others). Taken with any of these drugs, thioridazine may cause irregular heartbeats that could lead to death. This is not a complete list of drugs that may interact with thioridazine and cause heart problems.