Has anybody travelled, by bus, from Quito in Ecuador to Santiago in Chile?

How many days have you got? It's a hell of a journey. It can take anywhere from a couple of days,if all goes well,to five or more if you get problems with avalanches,rockfalls,floods,over-heating engines,bandits,false borders(highway robbery scam),the list goes on and on. It's hardly the safest way to do it,especially if you're on your own. Take as much survival stuff and food and drink as you can,and be prepared to work should the worst happen. The first bit is the worst,through Equador and the north of Peru.There are some good roads,and the scenery is fab,but it's a risky journey. It's OK when you get further south in Peru,pretty easy run from there,and safe. Terrific roads,even through the desert areas.You can get a shared taxi(collectivo) from Tacna(outside the main coach station) in the far south of Peru to Arica in the north of Chile. It's cheap and safe,and the driver will stand in queue with the passports for all the passengers so you get an easy time with the border. It's the easiest way to cross.The coach from there to Santiago takes around 21 hours. Great ride,but the bus is certainly not the best option all the way from Quito. You would be much better off flying,and it would probably be cheaper too,overall. You'll miss the fabulous scenery from the ground,but it's great from the air,too,and you'll have a much better chance of actually meeting your friend in Santiago. If you still want to use the bus,get a buddy. Team up with somebody before you board,and look out for each other. In Santiago,it's best to keep well away from the yellow (town) buses. Dangerous! Everything else is fine. Great place! You could see my answer on Santiago for that and other Santiago info.("Have you ever been to Chile?" 14th or thereabouts down the list) . The link below has flight info for Quito-Santiago. Best of luck.

mm from santiago de chile you could take many busses like tur-bus pullman-bus etc. all this busses are in the numerous station in santiago de chile,from right here u can holiday to Chile south or chile north good luck if u decide for tips touch me bye