2000 F250 V10 Triton engine, running rough?

On those, they had a habit of having coil packs that would go bad after a while and cause what you are describing so you definitely want to have the check engine light scanned (autozone in the US and I beleive Canadian tire in Canada do it for free)

However by your description, I'd also check for a vaccum leak at the PCV tube where it comes into the motor. as engine revs go up the amount of air through a leak affecting the mix decreases and why it may run better at higher RPMs

The tune up is something you can do but don't recommend without a torque wrench for a non-pro

The spark plugs if not torqued right have a habit of loosening and blowing out the hole. So if you feel uncomfortable, bring it to a pro

V10 Triton Engine

Sounds like a missfire or multiple ones. Do a code scann. Stalling at icle is a IAC valve. A tune up consists of new spark plugs ,at 100,000 miles

sure anyone can do a tune up on most any car or truck ... what you do is go to any parts store and say i need to do a tune up if you want to replace everything say a complete tune up but most likely you dont need it all done so thats where you have to guess at what you need or not need most likely just spark plugs but knowing what is bad will save you some money with parts but thsi link should help you some and going to parts store will get all you need for job parts or tools to do it an dthis web site wil lalso help you with about anything you need to replace or need to know about car care

well my papaw has that same truck and he loves it ive never heard it to do that it could be your transmission if its misfirein id check the transmission fluid and go through all the gears find which one it is misfirein on and take it to a professional