Stratocaster String Gague?

Right on! As you begin to increase the strength of gauge, you'll want to reinforce your Strat so as to not overload your bridge and cause it to pull out of position in an upward manner. This is easy though! Simply remove the back panel from your strat and take a look at the springs. Ideally, if you're going to move up in gauge, consider using at least four to five springs. Your Strat probably came out of the box with at least three springs. Go down to your local music store and pick up a few more springs and insert them symmetrically from one another. 10s won't really overload your bridge, but it sounds like you want to keep moving up. For instance, if you want to get to 13s live Stevie and Jimi-you'll need the spring fix.

Another thing, once you move to 10s, you'll need your guitar to be re-intonated which may require a tech unless you want to try. It's not too difficult if you have a chromatic tuner.