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how is the loss of blood compensated for?
In terms of maintaining filtration rate, a loss of blood could be compensated for by:
a) adjusting the afferent arteriole radius
b. adjusting the efferent arteriole radius
c. both of the above
d. none of the above
1 Answer
- 1 decade agoFavorite Answer
Hemorrhage leads to decreased blood pressure (hypotension) which leads to reduced filtration rate (GFR). The compensation for reduced GFR due to hypotension is mainly vessel diameter adjustment to increase Intra-glomerula pressure.
Under normal conditions, both the efferent and afferent arterioles are maximally dilated; in other words, changes to these two arterioles are essentially only constriction. Generally, constriction of one has the opposite effect on intra-glomerular pressure (iGP) than the other arteriole.
Constriction of the afferent arteriole reduces flow to the glomerulus, reducing iGP, reducing GFR. Constriction of the efferent arteriole increases iGP, increasing GFR.
The answer is to change the radius of the efferent arteriole to increase IGP to increase GFR to compensate for decreasing blood pressure.
Source(s): med school
