Yahoo Answers is shutting down on May 4th, 2021 (Eastern Time) and beginning April 20th, 2021 (Eastern Time) the Yahoo Answers website will be in read-only mode. There will be no changes to other Yahoo properties or services, or your Yahoo account. You can find more information about the Yahoo Answers shutdown and how to download your data on this help page.

Tim
Lv 4
Tim asked in Science & MathematicsMedicine · 1 decade ago

Seroquel?? for pathology class?

Is seroquel a SNRI? (serotonin-noreinephrine reuptake inhibitor)?

I'm having trouble understanding the affect seroquel has in increasing serotonin levels.

if its a receptor antagonist how does it increase serotonin levels?

could someone explain it to me?

Update:

I understand (Seroquel blocks the receptor by sticking to it, and preventing serotonin from binding to the receptor and turning it on.) but, how does that increase serotonin levels? and if it does how does it affect the body if the receptors are blocked??

4 Answers

Relevance
  • 1 decade ago
    Favorite Answer

    Seroquel (quetiapine) is a dibenzothiazepine atypical antipsychotic, not an SNRI. It has been proposed that this drug's antipsychotic activity is mediated through a combination of dopamine type 2 (D2) and serotonin type 2 (5-HT2) antagonism. It is an antagonist at multiple neurotransmitter receptors in the brain: serotonin 5-HT1A and 5-HT2, dopamine D1 and D2, histamine H1, and adrenergic alpha1- and alpha2- receptors; but appears to have no appreciable affinity at cholinergic muscarinic and benzodiazepine receptors. Norquetiapine, an active metabolite, differs from its parent molecule by exhibiting high affinity for muscarinic M1 receptors.

    Seroquel blocks the receptor by sticking to it, and preventing serotonin from binding to the receptor and turning it on.

    EDIT: Blocking serotonin receptors leads to an increased availability of serotonin in the synapse and raising levels.

    Source(s): Lexicomp Pharmacist
  • Anonymous
    5 years ago

    If you plan to live/work in an area with a high Spanish speaking population, Spanish will absolutely help you. If you're fluent enough in it (and maybe minoring in it in college would be good too) you may get paid more depending on where you work because they won't need to hire a translator. Anatomy is good, but the genetics course likely won't help you very much -- though by all means take it if it interests you! Parenthood/child development and anything that gives you experience working with children is also fantastic. As for going overboard with volunteering - if you think the experience is gold or that it will open doors for you to volunteer in college, go for it. Obviously, if it's fun for you, go for it. If not though, it may not benefit you too much as once you start applying for grad schools what you did in high school won't be relevant anymore. Good luck!

  • 5 years ago

    Latest FDA is to declare seroquel as non-effective and not indicated for dementia psychosis.

  • Anonymous
    1 decade ago

    seroquel is an antipsychotic

Still have questions? Get your answers by asking now.