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Tiffany H asked in HealthWomen's Health · 1 decade ago

Is there any correlation between blood type and a chromosome abnormality?

My mother has a chromosomal translocation. As a result, she suffered several miscarriages. My older sister inherited the translocation and also suffered several miscarriages. I am told I was tested at birth and that I inherited the same chromosome disorder. However, I have never been given proof that I have the same condition, and my mother is very dishonest and I have had no contact with her for a few years now, so it's hard for me to trust her word. I'm about two and a half weeks pregnant and terribly worried I will miscarry, but here's something I'm wondering: my sister and mother both have a different blood type than I do. I have my father's blood type, AB positive. Just wondering if there's a chance that I may not have the disorder since I don't have the same blood type my sister and mother do. Is there any correlation at all between blood type and a chromosomal translocation? Thanks.

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  • 1 decade ago
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    Chromosomal translocations are actually more common than people realize, but have absolutely nothing to do with blood type.

    It does however, put your baby at a higher risk of both a trisomy (an extra chromosome) and a monosomy (only one chromosome *** opposed to two). It would result inn a mosaic, meaning not a full extra chromosome, and the results would be less severe. (think trisomy 21 is Down Syndrome).

    But, there are very few trisomies and monosomies that are considered compatible with life, meaning that the baby can live and survive with them. Trisomy 21 is one of the only ones. There are a few others such as trisomy 13 and 18 that the baby may be born alive and may live up to a few years but they are never normal and require intense and frequent medical care. Most other trisomies result in the fetus dying, usually early in pregnancy, resulting in a miscarriage.

    You CAN get tested to see is what your mother says is true, but it would be very expensive and probably not covered by insurance. Also if you know what hospital you were born at, or where the test may have been done, you can request your medical records, usually for a fee, but it will be less than genetic testing.

    One thing to remember though, is that if it is true, there is nothing you can do to change it. The best thing you can do for you and your baby right now is relax and try to stress yourself out. Eat healthy and make sure that your baby gets what he/she needs to grow. Best of luck to you.

    Source(s): I'm a NICU nurse, and care for a lot of trisomies, also check out http://www.trisomy.org/ for more info.
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