Can you're VAC status change from cheating in an Single player game on Steam?

VAC only applies to online gaming. The only way you'd ever get a VAC ban is for using using hacks while playing online on steam servers.

Using cheat engines, mods, and the like on Single player games will have no effect on your VAC status.

However, it is against Steam TOS to hack a game .exe even it is single player. Don't worry though, it's likely you'll never need to do this, as hacking .exe's are usually done by people who want to steal source codes and crack games for pirating. It's is incredibly unlikely you'll ever need to hack a game .exe for the purpose of modding or cheating.

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RE:

Can you're VAC status change from cheating in an Single player game on Steam?

If one does find a way to cheat/mod/whatever in an single player game on steam, Can your VAC status/Steam account get into trouble for it? I'm talking about simple stuff like getting unlimited ammo by using Cheat Engine and stuff like that.

Oh, And please don't answer with stuff like...

Vac Status

no you wont i cheat in MW2 steam in private match you wont get banned the chances are like 0.0002%