Does replacing motherboard result in Loss of data in drive C?

No, replacing only the mobo never results in loss of data. However, it can mean you will not be able to boot the C drive if you have your OS installed on it because of the new hardware. The result will be a bsod (blue screen of death) or error while loading WIndows. I'd advice you toto backup all important data on the drive as you will have to reinstall your OS on the C: drive.

Hope this helps!

No. The data of Drives is stored in HDD, not in motherboard. The data won't be lost until you do a format. Even then if you are insecure about your data , you can use Windows Backup or any other backup software to backup your Drive C data in some removable storage media.

No it does not. ALL of your data is stored in a internal hard drive that is separate from your motherboard. However do make sure to take out the RAM and processor if you plan on using it on the new motherboard :)

No, C is the hard disk drive. it is a solid metal coated with a magnetic substance. Computers print the 1s and 0s on the hard disk. The hard disk only useful when the PC is on otherwise it's useless

No. Hard drive data will not be affected.

* No , HDD is different devices, But if u replaced motherboard u need to install drivers..

noo....ur data on harddrive...it doesnt related with motherboard

No!