Does this sentence make sense?

Yes, it does make sense. You have to use an adjective there (especial), not an adverb (especially). what makes it seem odd is that 'especial' is infrequently used as an adjective. It's a perfectly good word, but it's just not used as much as 'special' when an adjective is needed. For some reason, the adverb form 'especially' is used much more often than 'specially,' but again both are good words. Changing the word to 'special' would work well.

To those who maintain that 'especial' is not an English word, there's a marvelous thing called a dictionary. you should look at one every now and then. Just because you don't use a word does not mean it doesn't exist.

Especially does not fits well in this sentence. I'd use the word specifically or purposefully

Was this just standard love-making for Mack or was it _________ in regards to his love for Synthia?

In that sentence it must be "especially". In British English I would find the use of "especial" very rare (noted as non-existent by some respondents) - simply "special" as the adjective form. In the USA it might be more common, since many Americans do not use adverbial forms ending in "-ly".

Special not especial

There is no such word as "especial" in the English language - the word you need is "special".

Its just special, unique etc. Especial is not a word!

!!!!!!Especial is a word in English, and it is comparable to special.!!!!!!!

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No, especial isnt a word

...especial in regards to his love...

It is either 'with regard to'

or

'in regard to'.

I prefer the first.

no it is not correct use special instead of especial