I recently decorated a lacquer-sealed handmade wooden box with acrylic paints. What do I now seal it with?

Minwax brand has a polycrylic product that I have been using to seal acrylic painted items. It works great on fishing lures.

The label on a can of "Patricia Nimrocks Clear Acrylic Sealer" says that it is good over paint, lacquer and varnish. Since this is in a spray can, it would be a good choice to avoid brush marks.

Acrylic paint is pretty durable on its own.

My wife diluted acrylic paint with water based Varathane to decorate a play house. The decoration did fine for 25 years exposure to sun and rain until termites ate the wood.