Yahoo Answers is shutting down on May 4th, 2021 (Eastern Time) and beginning April 20th, 2021 (Eastern Time) the Yahoo Answers website will be in read-only mode. There will be no changes to other Yahoo properties or services, or your Yahoo account. You can find more information about the Yahoo Answers shutdown and how to download your data on this help page.
Trending News
How do I calculate time to steady state using half life of a drug?
A patient is diagnosed with hypertension and a drug, propranolol is prescribed – 40 mg three times a day. Propranolol has a half life of approximately 6 hours. After how many hours does propranolol reach steady state concentrations in the plasma?
For this I get 24-30 hours but then the question asks:
1) If propranolol is given at a dose of 60 mg twice a day – when would plasma steady state levels have been achieved? Would the potential for adverse effects be more or less with this regimen?
Also when
2) If 60 mg of propranolol had been administered 3 times a day what parameter would have changed? Time taken to reach steady state or the steady state level.
2 Answers
- ?Lv 77 years ago
"They gather in darkness, masterless and free...until they weave together to make Kingdom Hearts. And when that time comes, we can truly, finally exist."