Is there a possible way to practice short term memory loss on yourself or others?

I was pondering how writers, directors, and other artist have to rely on others to comprehend if their work is entertaining or not. So I thought that the creator could cause short term memory loss (depending if you can calculate "short term") to themselves after recording the purpose of the work to to be analyzed afterward with no memory of what the purpose was. Now obviously no harm can come to the future amnesiac so are there any ways to safely and accurately lose the memory of a day or two?