How to deal with OCD Coworker ?

It would be interesting to know whether she has actually been diagnosed with OCD. Some medical terms are used a lot these days by people to explain or excuse their behaviour, but unless the illness has been formally diagnosed I wouldn't take it as gospel that she has OCD, which stands for Obsessive Compulsive Disorder.

I have had to work with people who would not stop talking. It's tough if you can't get away from them. You can try saying "I can't concentrate properly if I talk while I'm working, so I'm afraid I can't talk to you right now." I've said that sometimes - "I can't work and talk, so I can't chat now," You may need to stonewall her questions - "Ask the manager. I need to get on with my work,." or something to that effect. If you keep it up long enough she will spend a lot of time crying, bad mouthing you and quite possibly having panic attacks, but if she is that ill with OCD she needs proper support, rather than limping along disrupting other people's work.

OCD is an anxiety related disorder. It isn't simple or quick to explain, but I suggest you look it up on Google and read about it, so that you will have some idea where your colleague is coming from, or whether she is excusing bad behaviour by giving it a medical name. It is quite possible that she is terrified of making an error which is why she keeps on asking for help with work that she should be able to do by herself. Excess talking can also be caused by social anxiety, nervousness, and self conciousness, but it may also simply be that she is a bad employee who is getting away with it by claiming she is ill.

This can sometimes be a hard issue to deal with, and sometimes it is hard for people with OCD to know when they are overdoing things. Perhaps you might want to try listening to music through headphones or something like that, or something that will distract you from her voice.