What's your top 10 (or 15) favorite anime and/or manga?

I can go first. For anime, Mushishi and One Piece are tied for first for me.

The others are, in no particular order:

Full Metal Alchemist: Brotherhood

Madoka Magica

Gungrave

Mononoke

Vampire Knight

From the New World

Girl who Leapt Through Time

Beast Player Erin

Fruits Basket

Fanstastic Children

Voices of a Distant Star

Lovely Complex

School Rumble

As far as Manga goes I really enjoyed Death Note, Claymore, and Gakuen Alice. I think all three are better in Manga form than in their anime form, if only because the plot had more room for the plot to grow as compared to their anime.