How will the Coronavirus Pandemic change globalism?

Stick around and see for yourself.

The small businesses are screwed, there's nothing for them in the long run.

I think what is going to happen is that there will be far more scrutiny with the transfer of people between countries. China has networks across the world and apparently these infectious diseases tend to originate out of there. 

What I am really concerned about is the introduction of small pox. (Russia has a weaponized version of the strain.) There is also ebola. (God forbid it ever becomes Category 4.)

not at all. The lockdowns mainly affect small businesses. The big ones are raking in billions, as people order stuff online