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Chemistry?

A critical reaction in the production of energy to do work or drive chemical reactions in biological systems is the hydrolysis of adenosine triphosphate, ATP, to adenosine diphosphate, ADP, as described by the reaction

ATP(aq)+H2O(l)⟶ADP(aq)+HPO2−4(aq)

for which Δ𝐺∘rxn=−30.5 kJ/mol at 37.0 °C and pH 7.0. Calculate the value of Δ𝐺rxn in a biological cell in which [ATP]=5.0 mM, [ADP]=0.90 mM, and [HPO2−4]=5.0 mM.

Δ𝐺rxn=

kJ/mol

Is the hydrolysis of ATP spontaneous under these conditions?

-yes

-no

1 Answer

Relevance
  • 6 days ago
    Favorite Answer

    Δ𝐺rxn = Δ𝐺∘rxn + RT ln Q

    In the calculation of Q, concentrations must be iMolar rather than mMΔ𝐺rxn = -30.5 kJ/mol + 8.314 J/molK (310 K) ln (0.005)(0.0009) / 0.005

    Δ𝐺rxn -48.6 kJ/mol

    Yes.

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