In this regard, what does it mean if somebody is having a conversation or discussion with somebody, and one of the members of the people involved in the discussion, conversation, says let's try to end this on a good note, let's try to end on a high note here.
Pearl
to leave it a positive experience
Beverly S
It kind of means with a good mood, happy people etc. No one angry.
Sunday Crone
That the conversation is getting controversial.
LiverGirl98
This usually suggests ending the conversation in a positive way, even if the two people disagree with the topic being discussed, or focusing on a positive that has come from the conversation.
Anonymous
That no one leaves with a negative opinion or attitude towards what has been discussed or towards those involved in the discussion.