What Body system/structure does diabetes affect?

It would be easier to list what it does not effect. Zero.

Your blood sugar is the fuel for your body. Everthing in your body needs fuel to replace and repair. From bones to skin.

The systems that most often break down first are eyes; high blood sugar causes macualr degeneration, lets just go with blindness instead of heavy details nerves; your nerve endings eventually deteriate and you will no longer feel your toes or the tips of your fingers circulation system; from your heart to arteries to veins get clogged and shut down.

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The pancreas, kidneys, liver, eyes, and feet usually get mentioned by an internalist. The risk of heart attack for a diabetic is the same as that for someone who has previously had a heart attack.

Diabetes can be controlled with a doctor's assistance, proper diet, and regular exercise to complement any prescribed medications taken as directed.

If you keep you blood glucose levels down then hopefully you can prevent any part of your body by being affected. But if you have poor blood glucose control then most of the body can be affected by diabetes. Eyes, kidneys,heart, nerves and blood circulation are amongst the most common affected. Diabetes can also slow down the healing of wounds and cause infections and in some cases gangrene to set in, so it is important to keep you blood glucose level under control

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Virtually all of them. Predominately, the eyes and feet. The controlling medications can have adverse affects on the heart, liver, and pancreas, among others.