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Could someone please translate the findings of this study into plain English?
There is a study located at http://ajp.psychiatryonline.org/cgi/content/full/1...
about VMAT2 binding sites being 31-42% higher in individuals with bipolar complex. Is this the reuptake transporter that is on the presynaptic neuron? How does the presence or absence of VMAT2 affect people? I understand that an increased amount of norepinepherine is linked to bursts of energy and is present during highs and a decreased level of seratonin is evident in lows. I really want to understand this biological correlation between the physical structure of the brain and bipolar complex.
2 Answers
- Anonymous1 decade agoFavorite Answer
i dunno what any of that means.
- 1 decade ago
"The main finding of this study was the observation that the concentrations of VMAT2 binding sites were higher in the thalamus and ventral brainstem of the patients with bipolar I disorder than in the healthy subjects, with mean differences between groups of 31% and 28%, respectively"
My thoughts on this, though I personally don't know what the different locations in the brain do, is that you should look up what VMAT2 is probably taking up in the thalamus and ventral brain stem. What chemicals are used to relay messages in the thalamus and ventral brain stem? The study just says that there are more of the reuptake transporters in these two places in the brain in bipolar people, so that means less of the chemicals present there.