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Sub protein amino acid sequences?
I read a lot about identical or near identical proteins coding sequences found in different species.
But I have not read anything about short amino acid sequences (10 to 20 codens maybe) used repeatedly in multiple large or complex proteins (perhaps 300 codens or larger.)
If we found short animo acid sequences which are used repeatedly, we could begin to understand the useful but incredibly complex chemical properties which even short animo acid sequence display despite their much simpler chemical properties by themselves. This would be real advancement rather than just ogle at how they twist around themselves.
Does anyone know of such research. Please don't bother explaining the use of G, C, A, (U in RNA and T in DNA) or tri-nucleotide codens or the coden - amino acid translation process. or the twenty or so amino acids. I am familiar with those. I want to know if we are looking at repeating sub protein animo acid sequences or only at inter-species whole proteins.
3 Answers
- NimrodLv 51 decade agoFavorite Answer
You need to re-familiarize yourself about proteins. It's codon, not coden.
The study of sequence similarity and conserved protein domains are already well established. They are called bioinformatics and proteomics. It is easy to determine the sequence of a protein and identify motifs that have known functions. It is possible to find a new protein and guess its function just from the primary structure. The HARD part is to figure out how they twist around themselves.
The primary structure (amino acid sequence) does not tell us how the chain will twist and fold into it's final shape. That requires X-ray crystallography and NMR, which is challenging to do for many reasons.
The website below has lots of info about protein domains.
Source(s): http://ca.expasy.org/prosite/ - ?Lv 45 years ago
It's generally accepted that >41 degrees C, most proteins will denature. However, it is different for each individual protein.
- 1 decade ago
i think the toxins of venoms in posoinous animals are short amino acid sequences..! a research was done by the 2007-harvard-scientist-of-the-year (ow my i forgot his name..!) about analyzing the protein sequences in poisonous sea snails (i even forgot the species' name..! shame on me..! :P) and applying them as commercial pain relievers..! i'm sorry i keep on forgeting the important stuff..! you could google it though, it's pretty famous..! =]