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Cytomegalovirus and glioblastoma link? Is there more research being done?
Thanks, April, but i am referring to this, "More than 80 percent of patients newly diagnosed with the brain cancer glioblastoma multiforme (GBM) exhibit detectable CMV in their blood as well as in their tumors..."
1 Answer
- aprilLv 71 decade agoFavorite Answer
Glioblastoma, there's ongoing research and many clinical trials for this almost ALWAYS fatal brain cancer. Cytomegalovirus, on the other hand, is a very common infection of the eye, also is a member of the herpes family.
Hmmm, a virus that's carried by about 80% of people worldwide. Now, if you're on chemo for gbm, you are more suseptible to the virus. It does NOT cause gbm.
From the same site you found that quote on: the fact that a vaccine based on CMV seems to have some effect on GBM, means the relationship has to be more than fortuitous:
There were 21 patients enrolled in the trial, and the vaccine appears to have delayed the re-growth of tumors from a typical six to seven months after surgery to more than 12 months. Early results also show a lengthened overall survival among GBM patients, from about 14 months with standard treatment to greater than 20 months.
Duke is a wonderful hospital, always on the cutting edge of breakthroughs with cancer.
This is an interesting link: http://www.news-medical.net/?id=31533
