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Is it safe to take heart medications, blood thinners, and blood pressure medicine with penicillin?

My grandfather was recently hospitalized for a 99% clogged artery. He survived, and he is doing well now, except that he is having some side effects from the medication he is taking. Particularly the medication Plavix.

He coughs constantly, and gets very dizzy very easily. My grandmother is worried that the combination of the mentioned medicines is not safe.

If it is safe, what could be causing these side effects? And how can he deal with them on a daily basis?

Thank you for answering.

8 Answers

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  • Anonymous
    1 decade ago
    Favorite Answer

    The cough and dizziness are most likely related to congestive heart failure. He may need his medications adjusted. Link at bottom list symptoms. Report the problems to his Cardiologist. Scream: REPORT THE PROBLEM TO HIS CARDIOLOGIST!

    Drug Interactions ( From Plavix)

    Study of specific drug interactions yielded the following results:

    Aspirin: Aspirin did not modify the clopidogrel-mediated inhibition of ADP-induced platelet aggregation. Concomitant administration of 500 mg of aspirin twice a day for 1 day did not significantly increase the prolongation of bleeding time induced by PLAVIX. PLAVIX potentiated the effect of aspirin on collagen-induced platelet aggregation. PLAVIX and aspirin have been administered together for up to one year.

    Heparin: In a study in healthy volunteers, PLAVIX did not necessitate modification of the heparin dose or alter the effect of heparin on coagulation. Coadministration of heparin had no effect on inhibition of platelet aggregation induced by PLAVIX.

    Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): In healthy volunteers receiving naproxen, concomitant administration of PLAVIX was associated with increased occult gastrointestinal blood loss. NSAIDs and PLAVIX should be coadministered with caution.

    Warfarin: Because of the increased risk of bleeding, the concomitant administration of warfarin with PLAVIX should be undertaken with caution. (See PRECAUTIONS–General.)

    Other Concomitant Therapy: No clinically significant pharmacodynamic interactions were observed when PLAVIX was coadministered with atenolol, nifedipine, or both atenolol and nifedipine. The pharmacodynamic activity of PLAVIX was also not significantly influenced by the coadministration of phenobarbital, cimetidine or estrogen.

    The pharmacokinetics of digoxin or theophylline were not modified by the coadministration of PLAVIX (clopidogrel bisulfate).

    At high concentrations in vitro, clopidogrel inhibits P450 (2C9). Accordingly, PLAVIX may interfere with the metabolism of phenytoin, tamoxifen, tolbutamide, warfarin, torsemide, fluvastatin, and many non-steroidal anti-inflammatory agents, but there are no data with which to predict the magnitude of these interactions. Caution should be used when any of these drugs is coadministered with PLAVIX.

    In addition to the above specific interaction studies, patients entered into clinical trials with PLAVIX received a variety of concomitant medications including diuretics, beta-blocking agents, angiotensin converting enzyme inhibitors, calcium antagonists, cholesterol lowering agents, coronary vasodilators, antidiabetic agents (including insulin), thrombolytics, heparins (unfractionated and LMWH), GPIIb/IIIa antagonists, antiepileptic agents and hormone replacement therapy without evidence of clinically significant adverse interactions.

    There are no data on the concomitant use of oral anticoagulants, non-study oral anti-platelet drugs and chronic NSAIDs with clopidogrel.

    Drug/Laboratory Test Interactions

    None known.

  • 5 years ago

    1

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  • 6 years ago

    This Site Might Help You.

    RE:

    Is it safe to take heart medications, blood thinners, and blood pressure medicine with penicillin?

    My grandfather was recently hospitalized for a 99% clogged artery. He survived, and he is doing well now, except that he is having some side effects from the medication he is taking. Particularly the medication Plavix.

    He coughs constantly, and gets very dizzy very easily. My grandmother is...

    Source(s): safe heart medications blood thinners blood pressure medicine penicillin: https://tinyurl.im/71Rio
  • 1 decade ago

    Plavix (clopidogrel) is a wonder anti-platelet drug. Most cardiologists like putting patients on this to prevent any further blockages, particularly if they have had a stent put in. However, some people do have side effects/ allergies to clopidogrel. Its best to inform your GP of these side effects because if he does have an allergy he needs it stopped. If so, aspirin may be used instead.

    Cardiac patients are put on a lot of tablets for different reasons; heart rate, blood pressure, blood thinning, water tablets- and can be taken at the same time. Just confirm with the GP that they are compatible

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  • ?
    Lv 4
    5 years ago

    3 years ago, I was diagnosed - hypertension with a reading of 160/100. I used to feel dizzy a lot, my legs had awful cramps, and levels were very low in my potassium, causing my fingers and toes to always cramp together. One day I started to feel really faint while I was driving with my daughter in the back seat and I passed out, hitting 3 cars and ending up in a ditch. That moment,I knew I had to do something because my meds weren't working. I heard about this diet from a friend and thought I'd give it a shot. The results have been remarkable. In just 21 days, I honestly can't remember feeling this good, my blood pressure went from 175/110 to 125/70.

  • Anonymous
    5 years ago

    You wouldn't be on a blood thinner unless you are so stationary that there is a possibility of blood clots forming. I was on blood thinners intravenously while in a coma. Blood pressure medicine would interfere with the blood thinner and you should follow the directions per your doctor.

  • 1 decade ago

    There are some blood pressure medications that can can cause him to cough. Could you please list all the medications he takes,thanks.

    Source(s): RN CCU
  • Anonymous
    1 decade ago

    go see your doctor he will know whats best

    hope he lives for many more years

    good luck:)

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