Best way to get down to NYC?

The best I can tell is to take Amtrak from Rochester to Penn Station in New York City. The on ways fare from Rochester to the city ranges from $55 to $78.

If you're looking for something cheaper, I would recommend take Amtrak to Poughkeepsie and then take Metro-North's Hudson Line from there to Grand Central. The one way fare from Rochester to Poughkeepsie will range from $48 to $68. A round trip off peak ticket from Poughkeepsie to the city wil cost you $29.

Once in the city, you can take the subway to your final destination in Queens. The fare on the subway is $2.25.

Good luck

Applanchain Trailways provide service from Rochester, NY to NYC PABT which cost $64, round trip cost $128.

2-Day Advance: $59 one way or $118 round trip.

7-Day Advance: $50 one way or $100 round trip.

http://www.trailwaysny.com/html/english/fares_pdf/...

MegaBus also offers bus service from Rochester's Eastview Mall to 28th St (1) Station.

http://us.megabus.com/

You could also take Greyhound Bus from Rochester to Port Authority Bus Terminal.

http://www.greyhound.com/home/

Ocean Travel, which is Chinatown Bus, where it operates one trip from Rochester, NY to NYC-Chinatown.

https://www.chinatown-bus.com/default.aspx

From these areas, you could take subway to Queens.

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