is there issues with my blood being drawn 76 times?

Any chance this is a phase I study? From your description, it sounds like they might be looking for some pharmacokinetic data (basically mapping out concentrations of the drug in your body at different time points after administration), so a high number of blood draws is not unusual in that circumstance. Hard to say if this is indeed what is going on, but I've seen it before. Whether or not your body can tolerate that many blood draws depends on exactly how much they're drawing each time, but this would usually be accounted for in the study design to ensure safety (studies are highly regulated to protect participants as much as possible).

The issue is having 25 blood transfusions...very, very risky. If you mean 25 blood draws...depending on your weight and/or general health, it could be risky. I hope if you decide to go through with this that a second, unbiased doctor is monitoring you. If you are on blood thinners or meds like anti-seizures it could play havoc with your blood levels. Be sure to drink a lot of fluids if you go through with it.

I am a little concerned that people would answer it is fine. I am a critical-care trained RN and it is not fine to say this without examining the person. Just because the studies may be legally entitled does not automatically mean it is safe, especially while testing a new drug. Let's say it is 3 cc times 25 tubes= 75 cc. that is 2 and a half ounces. That is a lot of blood. That could certainly affect blood levels if certain drugs one is on are involved or if say, the person has a low potassium to begin with. And 8 and a half ounces of blood over 3 weeks....if they weighed as little as my mom (104 lbs.,,,or lost a lot of weight during the 3 weeks)....and they are actually probably drawing 10-15 ccs or more each time, not just 3 ccs.

If you were to donate a unit of blood, that would be taking 450-500 cc of blood at one time. People do that routinely and safely.

With the blood draws being a week apart, you will have time to replenish the blood volume within a day (which you do by drinking water and staying hydrated), and some of the blood cells (you're always making new ones).

It looks like a lot of blood when it's yours and being removed, but you have plenty. The exception would be if you are already low on red cells (anemic) and it's unlikely that they'd accept you into the study if you were.

That is a lot of needle sticks. Hope you have really good veins.

Is this a study that will improve your health, or just an experiment? If an experiment, make sure they have explained exactly what they are doing, what they hope to learn, what the possible side effects / complications they know of might be, everything.

You will replace the blood drawn quickly. You will have sore arms and some bruises most likely. Get the tech that is most skilled at blood draws to be the one that works on you.

You are drawing blood, not donating blood. If you donate your blood 76 times you would end up as a bamboo.

Drawing blood is fine. They are legally certified to draw that many times. This means they have done a calculation to make sure you have enough blood to survive. They would have asked for age when you sign up for the drug test.

Donating blood is a whole different story. Two months gap for each donation.

It is fine. On an average scale it is fine. Taking up a drug test is a risk itself. Blood volume level replenishes within 24 hours. Biologically speaking, about 1/4 of the total cells in a human body are actually red blood cells. Committed stem cells develop into red blood cells every week. Once they have matured, a healthy adult can produce as much as 2 million red blood cells every second.

You will definitely feel sick or have an vasovagal episode(the feeling of being uneasy caused by the vagus nerve due painful or unpleasant stimuli as one of the causes.) when you have that much blood drawn. The human body will compensate the blood loss. Rest well eat well.

Also, though not related to your question, a healthy adult can draw as much as 16 ounces of whole blood at every one time provided that the next draw is 2 months later.

I'm pretty sure its safe if a doctor is doing it.. don't think they would do something to you that would be dangerous just for a test.

If your really that worried about it consult with a different doctor about it.