How long does it take to drive from North Carolina to Kentucky without stopping?

Raleigh NC to Lexington KY is about 8 hours without stopping.

Of course, it depends where in NC and KY. If you start at the two closest points, you can get from NC to KY in about 2 hours.

In order to give you anything close to an accurate reply we need the names of the cities.

From the NC state line to the KY state line traveling through Knoxville TN it's only 2 hours. From Wilmington on the coast to Owensboro KY on the Ohio River it's 12 hours.

Go to Google Maps. Select Get Directions. Type in the start point and the end point and read the results.

Sorry, but this is a really pointless question because you do not tell us the cities between which you want to travel. The time could be anywhere between 90 minutes to 5 hours or more.