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question about microsatellites (genetics)?
When observing microsatellites in a population of a certain animal what would be observed to show that there is high or low genetic variation? Im trying to understand what microsatellites would show to signify inbreeding within a population.
feel free to go as much in detail as you want
1 Answer
- Anonymous9 years agoFavorite Answer
It is really straightforward. Microsats are typically hypervariable, with many alleles per locus. If variation is reduced at several loci at the same time, then this signifies low genetic diversity, possibly due to inbreeding at some stage. Fallow deer in Europe are a good example - they typically have only 1 or 2 alleles at loci that have 10+ alleles in other deer species.
It is important that the effects are across multiple loci - one locus showing reduced variation is not informative - it may be linked to a locus under selection in that species, or another reason (e.g. mutation in the primer leads to null alleles).