Need help with the endocrine system.?

Prednisone is like a synthetic cortisol and has the same effects as it. When you take such drugs, your body treats it like a hormone and sees it as an increase, therefore creating a tolerance toward it and decreasing it's own secretion of cortisol. If one were to suddenly stop the medication, your body wouldn't be able to quickly adjust back to normal because it was used to you taking the supplemental hormone. Your body would then experience the effects having too little of the hormone, in this case adrenal insufficiency.

Cortisol steroid is secreted by the adrenal cortex during long-term stress.it increases blood glucose levels so that the muscles and organs can get delivered more of it. it also increases protein breakdown. it also decreases inflammation, which in turn could hurt the immune system by stopping the release of leukocytes (white blood cells) at the site of infection and inflammation.

What stimulates the adrenal gland to secrete the cortisol is the pituitary's secretion of ACTH. That hormone will indirectly release cortisol by stimulating the adrenal cortex to secrete it. Now if too MUCH cortisol is being released and your body notices this, negative feedback will occur and your pituitary will be signaled to STOP releasing anymore ACTH. Once ACTH is no longer being secreted, the adrenal cortex will no longer be activated, and cortisol levels will decrease and get back to normal. Once normal, the original endocrine process will start up if needed.