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5 Answers
- ?Lv 69 years agoFavorite Answer
Probably not.
Metabolism of Modafinil occurs in the liver, so it does not directly impact your kidneys the way some pharmy's like Ibuprofen do.
Medicine actually does not have a good model for how/why Modafinil works. It is considered safe for most people to take due to the low incidence and severity of side-effects plus the observable benefits on both wakefulness and circadian clock synchronization.
It's known the Modafinil directly impacts monamines and histamine in the hypothalamus. These neurotransmitters play dozens of roles in the body, including assisting in the regulation of blood sugar. Which is one way that Modafinil could theoretically impact your kidneys. Blood sugar is a key component of thirst and urine output.
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