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Is this about Telomeres true?
So basically Telomeres is in the ends of chromosones, and Aging occurs when we run out of telomeres. If we have too much of it, it can cause cancer/uncontrolled cell Growth.
1 DNA has 3.000.000 bases, and they make mistakes every 10.000.000 base.
Im not sure and i need to confirm, that I understand this. Thank you and please leave an answer which says what im a goner at or add relevant inf about them :)
They make Cancer a possibility when there is too much right?
They break the splitting cap from 50 when theyre too many to infinite, causing cancercells
?
1 Answer
- ThoughtLv 67 years agoFavorite Answer
You are forgetting half of the equation: telomerase.
Telomeres are the repeating sequences at the end of a chromosome. When the cell divides, the DNA replicates itself. The telomeres is a buffer that helps prevent necessary code from getting chucked in the process. Each time a chromosome gets replicated, about 100 base pairs of the telomeres are lost. When the telomeres gets too short, the cell can no longer replicate and thus dies via apoptosis.
Telomerase, on the other hand, goes along adding length to the telomeres sequence, thereby expanding the life of those cells.
What makes cancer "cancer" is that the cells do not undergo apoptosis properly: they replicate without end and the body can't kill them. Part of this is because telomerase is more active in cancer cells than normal cells (thus those cells replicate quickly and don't die). However, even if we could restore normal telomerase function to cancer cells (thereby making them "mortal" again), the cancer would still be bad for the body (it just wouldn't be growing, making surgical removal a more viable option).
