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Estimating Limit of Detection of analytical instruments?
As the title says, how could you ESTIMATE the limit of detection of HPLC and UV-Vis instruments, ONLY by looking at the signals of the lowest standard used and the blanks?
Thanks
P.S. Sorry about the caps lock, just want to make it clear that the question I need to answer asks for an estimate using the above method.
1 Answer
- 6 years agoFavorite Answer
Yes, you look at lower and lower standard until you find the one that is just statistically different than the noise/background. That is the LOD. There are formulas and procedures depending on the standard and type of instrument.
