if we use holy water to make holy spirit, would vampires die if they drink it?

In literature, they even do when sprinkled with it. But, as to turn the plot, some vessels with holy waters haven't been blessed by a real priest, or by a vampire who pretended to be a priest.

Have you considered hanging yourself publicly on facebook in protest against Trump?

No they would not, Because there is no such thing as a vampire..

U CANNOT MAKE THE HOLY SPIRIT WHO IS PART OF GOD, BUT GOD CAN GIVE A PORTION OF HIS SPIRIT TO THOSE WHO REPENT....CONSIDER PRAYING INSTEAD OF WASTING TIME ON GAMES...FOR vampires go to myths...TIRH

Wow.

Will a non-existent vampire-creature DIE, if it drinks the silly water that is for honoring non-existent god-creatures.

Hey, i think you're missing the point.

What's really important: will it kill Voldemort if he returns?

No. You're adulterating it in the fermentation process, and you might be adding some very unwanted pathogens since holy water is stagnant. But, I guess branch water is kind of stagnant too, and that's the best for making moonshine.