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jay
can someone please explain to me a little. It's my 3yo genetic test results?
COPY NUMBER VARIANT OF LIKELY BENIGN CLINICAL SIGNIFICANCE
INTERPRETATION:
An approximately 352 kb gain (duplication) of 4q35.1q35.2
was detected in this female.
This duplication involves multiple genes including 2 genes,
TLR3 and F11. Although these 2 genes have been reported in
autosomal dominant phenotypes. However, whole gene
duplications of each dominant gene or gains of this locus
have not been associated with a clinical phenotype. Further,
overlaps copy number gains of this locus or gains involving
each of the dominant genes have been reported in the general
populations of the Database of Genomic Variants
(http://dgv.tcag.ca)./ Thus, this result is interpreted as a
CNV of likely benign clinical significance.
Please expect the results of any other concurrent study in a
separate report.
NOMENCLATURE:
arr[GRCh37] 4q35.1q35.2(186965015_187317091)x3
Genes involved: TLR3, FAM149A, FLJ38576, CYP4V2, KLKB1,
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