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Skeletal muscle is striated (it has light-colored bands crossing it), and multiple nuclei. The muscle looks very highly organized when comparing it to smooth or cardiac muscle.
Cardiac muscle also may appear striated, but with only a single band crossing each bundle, the intercalated disc. Each cell possesses only one or two, large, round nuclei, which typically stain fairly dark.
Smooth muscle is not striated and each cell has only a single nucleus. The nuclei are typically very elongated and dark-staining and the cells are less organized than other forms of muscle