12 days late and wondering????

You took a test at a time when it could have detected a pregnancy (that is, after you missed a period) and it was negative. You also are suspected to have PCOS, which affects your hormones and can make it hard to get pregnant. And you just started some new medication. I think this is more likely to be connected to the PCOS and medication than to pregnancy. Here's why:

It's a little unusual to have PCOS and regular periods. Most of us have very irregular periods and that's our first clue that there's something wrong. That's not to say that you don't have PCOS since not all of us have the same symptoms--it's just different. My periods gradually got later and later until when I was finally diagnosed they were 3-4 months apart. It could be the PCOS affecting your cycle.

It could also be the metformin. PCOS is usually connected to insulin resistance, and metformin is a diabetes drug used in PCOS patients to regulate insulin function. It helps to get your blood sugar levels to normal and to get your body to use insulin properly. This is a good thing because with insulin resistance, you can have a lot of excess insulin in your body and it can cause the ovaries to produce too many androgens, or male hormones (resulting in PCOS). Metformin can help return ovarian function to normal and reduce your levels of male hormones, but that also means that your hormones might be changing a lot when you first start taking it. I went through all kinds of weird mood swings when I started it, until my body got used to it. You also need to know that if you don't ovulate regularly and you have PCOS, metformin is likely to cause you to start ovulating, making it more likely that you'll get pregnant.

I don't take spironolactone, but from reading about PCOS and talking to other women who take it, I know that it also messes with your hormones by reducing levels of androgens. So basically, you've just started taking two different medications that each affect your hormone levels, and your body is adjusting to them. It makes sense that your cycle might be affected until your body gets used to these medications. Incidentally, you really should not get pregnant while taking spiro--it can cause birth defects.

If you're interested in taking birth control pills, I would recommend them. Not only will they add protection from pregnancy, but they will also help with some of your PCOS symptoms. Particularly while you're on spiro, you need reliable contraception. PCOS can make it difficult to get pregnant, but there have also been women with PCOS who got pregnant accidentally, so you still have to be careful. Your risk of pregnancy is greater now that you're on metformin, because it can cause ovulation in women with PCOS. If you think you'd like to start taking the pill, talk to your doctor. I take Mircette, but Yasmin and Yaz seem to be the most common birth control pills for women with PCOS.

Bottom line, it sounds to me like your body is just getting used to the new medication and your cycles might reflect that. It's even more important to use reliable contraception while you're on these medications, though, so talk to your doctor about the pill or other forms of birth control. Take another home pregnancy test if it would help to reassure you. If you're still worried, call your doctor--better to know for sure what's going on than to sit around and be worried.

Spironolactone won't affect when your period comes. I've taken the brand form, Aldactone, for years. All that is is a diuretic that removes fluid directly from the abdomen. Metformin, better known as Glucophage, is an anti-diabetic that is also known to help make your body less insulin-resistant. If you have PCOS, they'll both help tremendously.

You could be under a lot of stress about the new diagnosis and meds. That will screw up your periods. Otherwise, give it a few more days and if it hasn't come, try another pregnancy test. If you still aren't pregnant, see your doctor again. The other thing that can do this is a ovarian cyst, but only your doctor can find that out.

Last month, like you, I was extremely late with my period. I was not pregnant. Sometimes our hormones just aren't kind to us.

Your suspected PCOS may be the culprit, because if you have PCOS, you're not ovulating like you should be. The medicine could also be the problem.

Still, it can't hurt to take a test again. If that shows up negative, then make an appointment with your OB/GYN to see what's up.

Good luck to you.

A lot of women have that problem. Last month I was freaking, being late again, when I am usually right on time. Went to the doc and she said not to worry, "if you are a month late, then come back in." Stress can cause you to be late too.

If the test has proved to be negative, you need not worry. The period get postponed for inexplicable reasons. Unprotected sex needs to be avoided.

take another test! but its best to go and see a doc so that they can take a blood test! the test can say negative when you are pregnant because the hormones detected in the test may be to low to actually show!

im not sure what PCOS is but you should contact your doctor to make sure youre not pregnant because now your taking meds and its a possibilty that they can harm your growing fetus. i would find out if also that the meds youre on can delay your periods. Call a doctor.

hi what you need to do is re do the test if it is still negative then go see your doctor , it also could be just the medication up setting your cycle what ever it is you still need to be checked out just in case you are pregnant, do it as soon as possible OK , i wish you luck

Medications can screw with your body. but you are twelve days late. call the Dr's office and ask for a blood test.. tell them of your situation and let them know your concerned. just hang in there. Please call the docs right now. don't wait it'll just drive you crazy. good luck...

You know, it STUNS me that so many have unprotected sex, and then wonder whats going on when their period is late. What did you expect?