are john cusack and joan csack related at all?

yes - they are brother and sister. Joan Cusack appeared in 10 of his movies: Class (1983), Sixteen Candles (1984), Grandview, U.S.A. (1984), Broadcast News (1987), Say Anything (1989), Grosse Pointe Blank (1997), Cradle Will Rock (1999), High Fidelity (2000), Martian Child (2007) and War, Inc. (2008).

PS. didn't you just love that movie?

I used to think that Joan Cusack was John Cusack in drag, but in fact Joan is John's older sister. There are also 3 other brothers and sisters who are actors, as is their father Dick Cusack.

Don't look alike? They could be twins!!! LOL. They're brother and sister. They appear in each other's movies quite often =]

Yes they are brother and sister. If you type in their names in yahoo search and go to the IMB link it will tell you their bios and everything you want to know about them.

They're brother and sister.

She's his older sister

brother and sister

Bro & sissy :)