My brother, a diabetic, has blood surgar over 300, dispite insulin and metformin. What is going on?

Is your bro a Type I or Type II? Probably Type II, since he's on metformin.

His body is not able to utilize the insulin which could be for a number of reasons, some of which may be beyond his control.

High blood sugars can be caused by eating too many calories, especially too many carbs, not exercising enough, and weighing too much.

He should be working with his doctor and a nutritionist and diabetes educator to learn how his body reacts to different foods. This means testing his glucose before and after meals, at bedtime, in the morning and any time he's curious about it.

By keeping a journal of foods and blood sugars, his doctor can adjust the medications to get his sugar under better control.

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I have diabetes just wanted to say...

over 300 for one is high and ot has to be treated well but its not a crisis so dont freak out.....I have over 300s once a week usally and all i do is take more insulin and ajust my rates so that they fit my blood suger needs .....if you need help with the adjstment than call the paerson that takes care of everything diabetes and they will help figure out a new plan based on you everyday life and what time of day.

If your brother is a teenager, very likely his hormones are interacting with other hormones. Testosterone binds to beef and pork insulin, and it also binds to human insulin, so the insulin cannot metabolize glucose like it should, resulting in high blood sugar levels. I went through almost every month from about 14 years old until I was almost completely post-menopausal, and every now and then I still can have a hormonal spike. I turn 56 years old in three days. (Yes, females produce testosterone too.)

He needs to work with a doctor or nurse practitioner to develop a better plan with the insulin - maybe give it at every meal/snack, or maybe take a different dosage. BUT BE VERY CAREFUL CHANGING AROUND THE DOSAGE BY HIMSELF - you have to be super aware when changing insulin. Explain to him how important it is to get his numbers better and why.

i dont have a answer i just want to say sorry