How often do I change the transmission fluid on my 2001 Acura TL?

On those vehicles, every 30K-45K miles.

The pre-2004 TL's and CL's were famous for disasterous transmission problems.

Acura Mdx Transmission Fluid Change

I have a 2000 Acura 3.5 RL with 226.000KLMs on the clock..IT'S had two cambelt replacements @ recommended mileage,along with the belt replacement,was also recommened,to drain gearbox,replace filter & oil after flushing the gearbox..SO i've had two belt replacements,as well as two oil & filter changes on the gearbox,three full brake pad,replacements & thats about it apart from tyres..IT still drives like new & thats pretty hard to beat..Enjoy your car the Acura's are magic look after it & it will return the favour..Stay well & enjoy your life..PS i'm with no 1 on this find a new mechanic,think the 1 you got has GNFI..

Those are well known for tranny failures as you already know. My advice change the fluid every 15,000 miles. It's pretty inexpensive at most independent shops. It's simply drain and fill. No pan and filter to change. That should help prolong it. Also, if your tranny has been replaced, and it was replaced after 3/2005, you have a redesigned tranny that should not have the failure problem.

Hi

ATX failure occurs when ATX fluid overheats that causes damage to temperature sensitive internals of an ATX

If ATX fluid is no longer RED and has a burnt smell to it, change it immediately completely with a flush and filter.

Also consider installing auxiliary ATX cooler (radiator) to significantly lower ATX operation temperature and prolong ATX life