My sister constantly lies?

Accept her for what she is--family, but not that trustworthy. Then look for people who you can be close to and who can nurture you, because you have suffered so many losses. You might find those people within your family, or outside your family. In the end, through the people we choose, we all make our own families. Good luck and don't give up.

"I am at a loss as to what I should do ?"

Make like she doesn't exist because her condition makes her that dangerous. Think of her as a stranger. You can't imagine how much suffering such a person can bring. Sky is the limit. She has a physiological problem. Treat your depression as the nervous system illness it is. Avoid toxins everywhere possible, especially scented things. Eat a whole food organic diet, if possible. Keep avoiding until your symptoms reduce. If that doesn't work, see a medical doctor. Good luck.

I have two brothers and the easiest way is to write them off. I even raised his two boys and got nothing from him but nonsense. but since she is family, so what. Like they say you make your bed sleep in t.

I'm sorry for your losses. The best thing to do is try to remember the good times that you had with them. remember, time doesn't heal anything, it's what you do for the time that counts. try to speak to your sister and share your feelings with her. I hope this helps.