Graves

In the following context, which solution will contain more human serum? the 5% or 40%?

"If the investigational product is highly protein bound, sponsors are encouraged to examine the in vitro antiviral activity of the investigational product in the presence of a series of dilutions of human serum up to 40 percent (e.g., 5 percent, 10 percent, 20 percent, 40 percent)"

Like being able to navigate both screens on my PC and laptop without having to use separate mouse

I'm aware that there are many web browser splitters, but I need something that can have an app that's already open to keep running even after I press the home button.

Alternatively, it can be something that allows me to split screen or float the app so that the app is not considered 'paused' or shut down by the system.

Any help?

I need some link/data relating to difference between leg muscle mass b/w rats, dogs, and humans. Any sources would be appreciated. I had no luck finding any

Except for cancer and fibrosis, where too much ECM/collagen is made

Can cancer cells grow and go through metastasis and form higher densities of ECM/collagen in vitro?

How does it work and what effects does it have on proline biosynthesis?

When a cancer cell uses glutamate to make proline by biosynthesis, does it still require tRNA and undergo same translation processes as in normal amino acid translation?

I'm not based in the US, but I would like to search for funding opportunities offered internationally by national gov or private investment organizations. Any sources would be helpful

I am looking for an extended-release depot forming injection drug that can be administered both ways

if the drug Abilify Maintena, an injection, has a prescribed dose of 400mg/mL in humans, what's the human equivalent dose in rats, monkeys, dogs, and rabbits? 

how do you get this number?

Human equivalent dose = HED

Human equivalent concentration = HEC

what's the difference between the two? how are the units mg/mL and mg/kg connected when it comes to drug dosage?

(1) is it reversible(recoverable)? if so, to what extent?

(2)why does the FDA approve licensing of drugs that have post-market incidents of necrosis? is it simply leveraging between the side effects and efficacy of the drug?ex. muscle cell necrosis by intramuscular injection from injection inflammatory reactions. 

are any of the two recoverable?

If two drugs share the same metabolic enzymes (ex. CYP or UGT), do they help one another or suppress metabolism of both?

for instance, if drug A is an inducer of Enzyme A, which drug B also uses in its metabolic pathway, will drug A help or reduce drug B's metabolism?

how can something travel in between liver, the bile duct, and intestine in human body?

for development of injectable drugs, how many sterilization steps does it need to go through in order to comply with the USP and EP guidelines? 

Is a single steam sterilization on the final packaged product enough, or should there be intermediary sterilization steps during the manufacturing process? 

are there any bioenhancers that you can attach to a molecule to specifically target the lung when given medication orally or through a IV or muscular injection? 

It's my understanding that Niclosamide is neither hydrophobic and hydrophilic enough for its clinical usage. What properties of the molecule are potential for manipulation to help its bio-availability upon injection?