Yahoo Answers is shutting down on May 4th, 2021 (Eastern Time) and beginning April 20th, 2021 (Eastern Time) the Yahoo Answers website will be in read-only mode. There will be no changes to other Yahoo properties or services, or your Yahoo account. You can find more information about the Yahoo Answers shutdown and how to download your data on this help page.
Trending News
Do Biosynthesized Amino Acids still need tRNAs?
When a cancer cell uses glutamate to make proline by biosynthesis, does it still require tRNA and undergo same translation processes as in normal amino acid translation?
2 Answers
- SmegheadLv 79 months agoFavorite Answer
Your question is confused. tRNA is not used to MAKE amino acids; it is used to USE amino acids. tRNA is required to take an amino acid and put it into a protein. It doesn't matter whether the amino acid is made by the cell or absorbed from your food or whatever. It also doesn't matter if the cell is cancerous or not. tRNA is still needed during translation to get the amino acid into your protein.
- Ted KLv 79 months ago
Short answer is NO.
Translation refers specifically and strictly to synthesis of proteins--the stringing together of amino acids by the translational machinery (including mRNA, tRNA, ribosomes, etc).
Biosynthesis of the amino acids themselves is a separate process from translation. It involves chemical modifications to various carbon skeletons of intermediates from metabolism.
Cancer cells do both of those the same way non-cancer cells do, although some of the regulatory processes which modulate them have been undone or aren't working.