Does any liquor have to be refirgerated after the bottle is opened?

jagermeister

The shelf lives of liqueurs are more temperamental than the base spirits because they contain sugar and other ingredients which can spoil, some more than others. Most opened (and well sealed) liqueurs should last for months and even years depending on their alcohol content and preservatives. Again, opened bottles are likely to lose some of their characteristics due to exposure to air. Once you begin to see any sugar crystallizing on the bottom, discoloration, curdling or other changes you will want to throw that bottle away or at least give it a taste test before mixing with it.

Cream liqueurs, those that contain dairy, cream or egg, are a different story and should be discarded after 18 months or so. Liqueurs like Bailey's Irish Cream, Advocaat and Amarula should be consumed within a year of opening, although some of their cheaper creamy cousins will deteriorate faster. Even in unopened bottles, these liqueurs will spoil and be undrinkable after a year and a half or more. Some of these touchier liqueurs will include an expiration date on the bottle as well. It is unnecessary to refrigerate cream liqueurs, but it can't hurt either

Cream liquors, as the above poster mentioned, and Vermouth (and other fortified wines). Vermouth, as a fortified wine, will go bad just like an opened bottle of wine will, but it takes a little longer due to the higher alcohol content. Unrefrigerated it'll last a week once opened, about a month in the fridge.

Incidentally, that's a reason a whole lot of people shun vermouth in drinks- becuase people keep vermouth out, it goes bad, and makes a drink taste bad when added to a drink. Don't let bad martinis happen to you.

If you mean 40% ABV spirits then no.

If you are talking about liqueurs instead of liquor then only cream based onces need refridgerating

Usually I only refrigerate Cream based drinks like Baileys Irish Cream. ♥