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Microscopic Cancer Cells Found Two Weeks After Finishing Chemo?

My mom has stage 3 uterine cancer and after total hysterectomy, she received 5 weeks radiation, 4 low chemo, then 3 heavy chemo of Carboplatin with Taxol 3 weeks apart. She had her last chemo on April 29th, then mid May was in the hospital where they found fluid build up.

Come to find out there were microscopic cancer cells still there, and she will need three more treatments, once a month, this time with Avastin and Doxcil. The good thing is her CT scan showed nothing, also blood tests were all good, but still these microscopic cells causing fluid build up.

I found it strange that there would still be cancer cells so soon after receiving the first chemo treatments, has anyone else heard of this, does this mean that the first set never worked or she just needs more to finish getting what the first set could not get?? Could chemo cause fluid build up too??

If anyone has heard of anything similar or knows something about this, any info is much appreciated.

Update:

The doctor said her tumor had punctured through the uterine wall and attached to one ovary, so they removed all her reproductive organs. Before they started her chemo, there was no fluid, nothing. They said they would do rad and chemo "just in case" there were any cancer cells left.

Is it not strange that there would be fluid after chemo, but none before chemo started, when they first found the cancer??

Update 2:

The reason I said microscopic is because she has no tumors only the actual cells on the microscopic level, meaning that they are so small nothing shows up on CT scan.

5 Answers

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  • Q
    Lv 7
    10 years ago
    Favorite Answer

    Chemo generally kills cells while those cells are dividing. Since cancer cells grow very quickly, they divide really often and therefore are killed much more readily than you body's own normal, healthy cells, which divide less often. The higher the dose of chemo, the more it will kill. But they can't give you a super high dose because it will kill too many of your good, normal cells as well as the cancer cells. It already kills a lot of healthy cells that divide often, which is why you've got problems such as vomiting (stomach lining cells killed) and low red and white blood cell counts (bone marrow killed). With each dose of chemo, more and more of the cancer cells are killed. Unfortunately, some cells can be missed, either because they have immunity to the chemo (cells do develop immunity over time) or because they weren't dividing at the right moment when the chemo was in your body. It's hoped that one's own immune system will kill off that small number of remaining cells (though the immune system has been seriously weakened by the chemo itself). Unfortunately, in your mom's case, there was a visible number of cells that were not killed, even though the chemo did kill a large amount of them. Hopefully the Avastin and Doxcil will be able to kill off the remainder of the cells. All of the large pieces of tumor have been killed off already, and that's why there's nothing on the CT scan.

    It's not the greatest news that there is still microscopic tumor cells and that she's got fluid buildup. You might want to get a second opinion from another gynecologic oncologist about the cell type, to make sure she's having the best chemos for her situation.

  • Anonymous
    4 years ago

    Microscopic Cancer Cells

  • 10 years ago

    There are over 50 different types of chemo and different cancers respond differently to each one. Unfortunately, there is no cure for cancer so even with chemo and radiation, the cancer can still be there. I had radiation, and still have cancer. In order to kill the cancer cells, they have to get the radiation or chemo into the cells. Sometimes the cells don't absorb the the chemo or radiation. For me, my cells have to be starving of a certain substance, the radiation bonds with that substance and then the cells absorb it. However, if the cells are not starving for it, then they won't absorb it and die. This is why cancer treatment can be very challenging. My oncologist told me that cancer cells at the microscopic level are the most stubborn to get. That is why there are a lot of re occurrences of the cancer. I am sorry about your mom's cancer. Just keep listening to the doctors, and being there for her.

  • 10 years ago

    Sometimes the cancer does not respond well to certain chemo cocktails and the doctors will try other meds

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  • Anonymous
    10 years ago

    I am not really following you. All cells are microscopic.

    Are you saying the ascites was positive?

    I’m not sure which stage 3 she has, but the cancer has already spread outside the uterus making it impossible to know when or if every cancer cell has or will be destroyed.

    I’m sure her doctors hope there would be no evidence of disease with the treatment she has already received.

    Source(s): I am a cancer registrar.
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